Millionaire Project
By Jack Duffin, Jason Franks, Peter Hunt, Kyle Jones, Ronan Shaffer
Unmet need: The natural cure for cancer through proteins in cancerous cells.
Project Idea: To use TIC10 as a natural tumor resistor.
Materials needed:
TRAIL stands for Tumor necrosis factor-related apoptosis-inducing ligand or Apo 2 ligand.
Background on TRAIL
TRAIL is a member of a tumor killing molecule family thats job is to initiate apoptotic suicide. TRAIL is a unique molecule because it kills only transformed cells, not normal cells. TRAIL is not completely effective because some tumors have developed TRAIL resistance. Apoptosis produces cell fragments called apoptosis bodies that phagocytic cells engulf and quickly remove the contents of the cell.
Problem
Why do some tumors to develop TRAIL resistance?
Solution
As amateurs in this area of science, I believe that we would not be able to figure out why some tumors develop resistance to the TRAIL protein. What we can do is create a laboratory where we give the best scientists the opportunity to solve this problem. IDEA - Combine a resistance protein with the TRAIL protein.
Facilities needed to make Materials.
Estimated cost of development
How many units should be made for the market
As many as possible.
Timeline (production and time to develop product)
Market (who will be buying this)
Anybody who has cancer will be buying our product.
Bibliography
http://www.nature.com/onc/journal/v22/n53/full/1207232a.html
By Jack Duffin, Jason Franks, Peter Hunt, Kyle Jones, Ronan Shaffer
Unmet need: The natural cure for cancer through proteins in cancerous cells.
Project Idea: To use TIC10 as a natural tumor resistor.
Materials needed:
- lab (need sq feet)
- tumors
- vector (mice)
- 50 mg of TIC-10 - $350
- 100 micrograms of active human TRAIL protein - $198
- scientists
- employees
TRAIL stands for Tumor necrosis factor-related apoptosis-inducing ligand or Apo 2 ligand.
Background on TRAIL
TRAIL is a member of a tumor killing molecule family thats job is to initiate apoptotic suicide. TRAIL is a unique molecule because it kills only transformed cells, not normal cells. TRAIL is not completely effective because some tumors have developed TRAIL resistance. Apoptosis produces cell fragments called apoptosis bodies that phagocytic cells engulf and quickly remove the contents of the cell.
Problem
Why do some tumors to develop TRAIL resistance?
Solution
As amateurs in this area of science, I believe that we would not be able to figure out why some tumors develop resistance to the TRAIL protein. What we can do is create a laboratory where we give the best scientists the opportunity to solve this problem. IDEA - Combine a resistance protein with the TRAIL protein.
Facilities needed to make Materials.
- lab (need sq feet)
Estimated cost of development
How many units should be made for the market
As many as possible.
Timeline (production and time to develop product)
Market (who will be buying this)
Anybody who has cancer will be buying our product.
Bibliography
http://www.nature.com/onc/journal/v22/n53/full/1207232a.html